Keywords

• Glyx-13
• White Powder
• 117928-94-6

Quick Details

• ProName: Peptide Powder Glyx-13 CAS 117928-94-...
• CasNo: 117928-94-6
• Molecular Formula: C18H31N5O6
• Appearance: White powder
• Application: GLYX-13 is a long lasting and rapid ac...
• DeliveryTime: 1-3days after Payment
• PackAge: plastic bottle
• Port: Shanghai
• ProductionCapacity: 100 Gram/Month
• Purity: 99%
• Storage: Keep in a cool, dry, dark location in ...
• Transportation: By express. FedEx, DHL, DPD, UPS, NL P...
• LimitNum: 1 Gram
• Grade: Pharma Grade
• 117928-94-6: Glyx-13
• white powder: peptide

Superiority

Company Profile

Shanghai Chinqesen Biotechnology Co., Ltd.
Company slogan: Innovation, cooperation and win-win
Company introduction: Shanghai Chinqesen Biotechnology Co., Ltd. is a professional pharmaceutical technology company, dedicated to the R&D, production and sales of peptides, pharmaceutical raw materials, pharmaceutical intermediates, and fine chemical intermediates.
Company team: Shanghai Chinqesen Biotechnology Co., Ltd. has a strong technical background. The team members are all PhD, master and undergraduate students. Good at the process route design, synthesis, process optimization and new drug research of drugs and chemical intermediates. At the same time, the company is equipped with various advanced HPLC-MS, GC-MS instruments and organic synthesis detection equipment, which can meet the detection needs from milligram level to kilogram level. 

1, High quality with competitive price:
2, Fast and safe delivery
3.Excellent pre-sales and after-sales service
4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 years

Details

Quick Detail

Product Details : GLYX-13 
CAS: 117928-94-6
MF: C18H31N5O6
Sequence:  Thr-Pro-Pro-Thr-NH2
Synonyms GLYX 13;L-ThreoninaMide, L-threonyl-L-prolyl-L-prolyl-;GLYX-13 trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate;Thr-Pro-Pro-Thr-NH2 trifluoroacetate;TPPT-amide trifluoroacetate;Rapastinel;GIYX-13
Purity: 99.0%
Appearance: White Powder
Minimum Order Quantity: 1 g
Test Method: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below-18° C. 

What is Peptide GLYX-13

Rapastinel (GLYX-13) is a NMDA receptor modulator with glycine-site partial agonist properties. It is a robust cognitive enhancer and shows rapid and long-lasting antidepressant properties in both animal models and in humans.
 
Rapastinel was derived from a monoclonal antibody, B6B21, is a tetrapeptide (threonine-proline-proline-threonine-amide) obtained from amino acid sequence information obtained from sequencing one of the hypervariable regions of the light chain of B6B21. The in-vivo and in-vitro pharmacology of rapastinel was examined.

GLYX-13 Peptide Benefits

Rapastinel was found to be a robust cognitive enhancer in a variety of learning and memory paradigms and shows marked antidepressant-like properties in multiple models including the forced swim (Porsolt), learned helplessness and chronic unpredictable stress.

Rapastinel's rapid-acting antidepressant properties appear to be mediated by its ability to activate NMDA receptors leading to enhancement in synaptic plasticity processes associated with learning and memory.

This is further substantiated by the increase in mature dendritic spines found 24 hrs after rapastinel treatment in both the rat dentate gyrus and layer five of the medial prefrontal cortex. Moreover, ex vivo LTP studies showed that the effects of rapastinel persisted at least two weeks post-dosing.

GLYX-13 Peptide Mode of Action

1. Enhance mental intelligence;
 
2. Boost memory and leaning capabilities;
 
3. Improve brain power to solve problems and protect it from any chemical or physical injury;
 
4. Enhance motivation level;
 
5. Enhance the control of cortical/subcortical brain mechanism;
 
6. Improve sensory perception.

Description

Rapastinel is a novel antidepressant drug approved as an adjunctive therapy for the treatment of treatment-resistant

major depressive disorder. It is a centrally active, intravenously administered (non-orally active) amidated tetrapeptide

(Thr-Pro-Pro-Thr-NH2) that acts as a selective, weak partial agonist (mixed antagonist/agonist) of an allosteric site at

the glycine site of the NMDA receptor complex (Emax ≈ 25%).

The drug is a rapid-acting and long-lasting antidepressant as well as robust cognitive enhancer by virtue of its ability

to both inhibit and enhance NMDA receptor-mediated signal transduction.

Application&Function

GLYX-13 is a long lasting and rapid acting antidepressant. Investigational drug for the treatment of depressive disoder.

GLYX-13 trifluoroacetate has been used as an activator of NMDA (N-methyl-D-aspartate) receptor.

Our Advantages

1. Professionalism of production: With more than 20 years of experience in peptide production, to ensure the stability and reliability of each batch of peptide quality.
2. Professionalism of product efficacy: We are familiar with more than 300 kinds of cosmetic peptides that are now available worldwide, thorough research.
3. Professionalism of service: customer satisfaction is our greatest work.
4. Reliability: We always believe that only good reputation and product quality can make a good company.
5. Flexibility: We offer a variety of peptides, liquid, freeze-dried powder etc.
6. Variety products: We offer more than 200 peptides, including dipeptide, tripeptide, tetrapeptide, pentapeptide, hexapeptide, copper peptide, oligopeptide and so on.

FAQ

Q1: May I get one sample before placing order
Re: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.

Q2: Which payment is available for your company
Re: T/T, ,Bitcoin etc. You can choose the one which is convenient for you.

Q3: How and when can I get my goods after payment
Re: For small quantity products, they will be delivered to you by international courier(DHL, FedEx, TNT etc.) or by air. Usually it will cost 3-10days that you can get the goods after delivery.For large quantity products, shipping by see is worthwhile.It will cost 15 to 30 days to come to your destination port, which depends on where the port is.

Q4: Is there any possible to use my appointed label or package
Re: Yes. If needed, we'd like to use label or package according to your requirement.

Q5: How can you guarantee the goods you offer is qualified
Re: We always believe honesty and responsibility are basis of one company, so whatever products we provide for you all are qualified. We will have goods tested and provide COA before delivery for sure.